N-[(1,1-dimethylethoxy)carbonyl]-L-leucine
N-[(1,1-dimethylethoxy)carbonyl]-L-leucine
CAS: 13139-15-6;200936-87-4
Molecular Formula: C11H23NO5
N-[(1,1-dimethylethoxy)carbonyl]-L-leucine - Names and Identifiers
N-[(1,1-dimethylethoxy)carbonyl]-L-leucine - Physico-chemical Properties
| Molecular Formula | C11H23NO5 |
| Molar Mass | 249.30402 |
| Melting Point | 85-87°C(lit.) |
| Boling Point | 356°C at 760 mmHg |
| Specific Rotation(α) | -25 ° (C=2, AcOH) |
| Flash Point | 169.1°C |
| Vapor Presure | 4.98E-06mmHg at 25°C |
| Appearance | White powder |
| Color | White |
| Storage Condition | Store below +30°C. |
| MDL | MFCD00066067 |
| Use | Used for biochemical reagents, peptide synthesis. |
N-[(1,1-dimethylethoxy)carbonyl]-L-leucine - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 2924 19 00 |
N-[(1,1-dimethylethoxy)carbonyl]-L-leucine - Introduction
N-Boc-L-leucine is a common amino acid derivative, often in the laboratory in the form of a hydrate. Here is the relevant information:
Nature:
N-Boc-L-leucine hydrate is a colorless crystalline solid that is readily soluble in water and some organic solvents, such as methanol and acetonitrile. It has a relatively high melting point and stability.
Use:
N-Boc-L-leucine hydrate has important applications in the field of organic synthesis. It is often used as a starting material for the synthesis of chiral compounds and an important chiral inducer for the construction of chiral centers. In addition, the compounds are also used in the synthesis of biologically active molecules, such as pharmaceuticals and pesticides.
Preparation Method:
N-Boc-L-leucine hydrate is generally prepared by reacting N-Boc-L-leucine with a suitable hydrating agent. Common hydrating agents include anhydrous ethanol, water, or other solvents.
Safety Information:
N-Boc-L-leucine hydrate is generally safe under normal conditions of use, but the following points should be noted:
1. Good laboratory operation measures should be taken during preparation and handling to avoid direct contact with skin and eyes.
2. avoid inhaling its dust or solvent vapor, and maintain good ventilation in the workplace.
3. Wear appropriate personal protective equipment, such as lab gloves and goggles.
4. Store should be sealed to avoid contact with oxygen, moisture and other chemicals.
It should be noted that the above information is for reference only, and the specific use and safe operation should be evaluated and stipulated according to the specific experimental conditions and product description. If specific experimental operations are required, it is recommended to conduct them under the guidance of an experienced chemical laboratory or professional.
Nature:
N-Boc-L-leucine hydrate is a colorless crystalline solid that is readily soluble in water and some organic solvents, such as methanol and acetonitrile. It has a relatively high melting point and stability.
Use:
N-Boc-L-leucine hydrate has important applications in the field of organic synthesis. It is often used as a starting material for the synthesis of chiral compounds and an important chiral inducer for the construction of chiral centers. In addition, the compounds are also used in the synthesis of biologically active molecules, such as pharmaceuticals and pesticides.
Preparation Method:
N-Boc-L-leucine hydrate is generally prepared by reacting N-Boc-L-leucine with a suitable hydrating agent. Common hydrating agents include anhydrous ethanol, water, or other solvents.
Safety Information:
N-Boc-L-leucine hydrate is generally safe under normal conditions of use, but the following points should be noted:
1. Good laboratory operation measures should be taken during preparation and handling to avoid direct contact with skin and eyes.
2. avoid inhaling its dust or solvent vapor, and maintain good ventilation in the workplace.
3. Wear appropriate personal protective equipment, such as lab gloves and goggles.
4. Store should be sealed to avoid contact with oxygen, moisture and other chemicals.
It should be noted that the above information is for reference only, and the specific use and safe operation should be evaluated and stipulated according to the specific experimental conditions and product description. If specific experimental operations are required, it is recommended to conduct them under the guidance of an experienced chemical laboratory or professional.
Last Update：2024-04-09 15:17:51
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View History
N-[(1,1-dimethylethoxy)carbonyl]-L-leucine
2-[(2-methylphenyl)methyl]-6-[(E)-2-phenylethenyl]-2,3,4,5-tetrahydropyridazin-3-one
柏木双黄酮
(R)-A,A-BIS(3,5-DICHLOROPHENYL)-2-PYRROLIDINEMETHANOL HYDROCHLORIDE
ISOTHEBAINE
NDE II
tert-Butyl (2S)-2-(2-hydroxyethyl)piperidine-1-carboxylate
(S)-1-(1-羟基-3,3-二甲基丁烷-2-基)-3-均三甲苯基-4,5-二氢-1H-咪唑-3-鎓六氟磷酸盐
四氰基镍(II)酸钾水合物
1,3-Dioxol-2-one, 4-(hydroxymethyl)-5-methyl-
2-[(2-methylphenyl)methyl]-6-[(E)-2-phenylethenyl]-2,3,4,5-tetrahydropyridazin-3-one
柏木双黄酮
(R)-A,A-BIS(3,5-DICHLOROPHENYL)-2-PYRROLIDINEMETHANOL HYDROCHLORIDE
ISOTHEBAINE
NDE II
tert-Butyl (2S)-2-(2-hydroxyethyl)piperidine-1-carboxylate
(S)-1-(1-羟基-3,3-二甲基丁烷-2-基)-3-均三甲苯基-4,5-二氢-1H-咪唑-3-鎓六氟磷酸盐
四氰基镍(II)酸钾水合物
1,3-Dioxol-2-one, 4-(hydroxymethyl)-5-methyl-